COSMIC Annual Meeting. An impression

21-25 January, 2019
Workshop Systems Medicine
On 21 January 2019 we kicked off with the Workshop Systems Medicine and computational modelling. The lecturers talked about Systems medicine, ordinary differential equations, stochastic modelling, Gillespie algorithm, agent-based modelling, protein functional interaction networks, gene regulatory network interference. 
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The ESRs are listening to a lecture of Sebastian Binder
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Sebastian Binder talks about a agent based model about wolves that eat sheep.
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Judith Farres talks about protein interaction networks and how they can be used to study disease.
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Olivier Gandrillon talks about computational approaches for gene regulatory network interference
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 Maria Martinez introduces the ESRs to noise and stochastic modelling.
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 Finalizing the workshop Systems Medicine with a very nice dinner in Amsterdam
Workshop Advanced experimental methodologies in Immunology
On 22 January 2019 we continued with the Workshop Methodologies in Immunology. Presentations about antibody technology, advanced imaging technologies, advanced Flow-cytometry and novel FACS applications, high throughput analysis of BCR and TCR repertoires, transcriptomics and Epigenetics (single-cell & long-read), and transgenic, reporter and knockout mice in immunology.
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Jeroen Guikema talks about antibody technology
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Prof. Eric Reits (Cell Biology, AMC) talks about Advanced Imaging technologies in Immunology.
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Berend Hooijbrink talks advanced Flow-cytometry and novel FACS
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Dr. Andreas Agathangelidis & Prof. dr. Niek de Vries (MD) explain repertoire sequencing of T-cells and B-cells

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Martin Turner explains transcriptomics and epigenetics (single-cell & long-read) approaches
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Rikard Holmdahl and Stefano Casola explain the development and use of transgenic, reporter and knockout mice in immunology
During this workshop the ESRs also attended a patient seminar during which a patient with rheumatoid arthritis was interviewed by Niek de Vries. Through this interview the ESRs were informed about the experience of a patient with a severe form of this disease.
Mid-term review meeting
On 23 January 2019 we continued with the mid-term review meeting during which the EU project officer (Charalampos Moschopoulos) and the COSMIC External Advisory Board were also present. During this meeting the coordinator gave an overview over COSMIC and its current status. Subsequently, the ESRs briefly presented their research projects. Finally, the Project Officer had a private meeting with the ESRs while the PIs and the External Advisory Board discussed various organizational aspects of the project, and received first feedback from the EAB. The feedback received from the EAB was positive although they advised to put more effort to link to experimental work with the computational modelling. The Project Officer was also positive about COSMIC but stressed to keep an close eye on the implementation of the seconment program and to finalize the consortium agreement. 
Annual meeting
On 24 January 2019 we continued with the annual meeting during which the PIs gave a short update about the research they were planning to do with their ESR(s). Subsequently, the research projects were discussed in smaller groups. Impresssion of the meeting:
Workshop Modern Research: Open Science and Advanced ICT
On 24 January 2019 we concluded the week with a Workshop about modern research. We had several very interesting talks and discussion about various aspects of scientific projects. The workshop was concluded with a tour at the national computer center SURFsara in Amsterdam. Antoine van Kampen kicked-off with a presentation about Open Science in which we had interesting discussion about open access publishing and data.
Very tired after a stressfull night
We had a very interesting and entertaining presentation (Clinical Data Reuse or Secondary Use: Current Status and Potential Future Progress) from Prof. dr. Christian Lovis of the University of Geneve. One thing he talked about was the correlation between chocolate consumption and number of nobel Laureates (published in the high impact journal the New England Journal of Medicine)
Dr. Jan Willem Boiten from Lygature talked about working successfully in public-private consortia 
New business models for health Prof. dr. Anwar Osseyran University of Amsterdam / SURFsara
Subsequently, the group went to the Data Tower where they got a guided tour at SURFsara by Dr. Carlos Teijeiro Barjas.  After a check of our ID and giving away our finger print we could enter the building. An impression is shown below. 
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